Nature Communications | Apr. 29, 2020 Intron Retention Is a Hallmark and Spliceosome Represents a Therapeutic Vulnerability in Aggressive Prostate Cancer The role of dysregulation of mRNA alternative splicing (AS) in the development and progression of solid tumors remains to be… Read More
Xenobiotica | Apr. 2020 Correlation of the in vitro Biotransformation of H3B-6527 in Dog and Human Hepatocytes With the in vivo Metabolic Profile of 14 C-H3B-6527 in a Dog Mass Balance Study 1. H3B-6527 is an orally available covalent small molecule inhibitor of FGFR4 undergoing evaluation in adults with hepatocellular carcinoma. Absorption,… Read More